An update on some structural aspects of the mighty miniwall.

CAR T-cell Therapy of Hematologic Malignancies: An Update in Targeted Antigens

Immunotherapy with genetically engineered T-cells that express the chimeric antigen receptor (CAR) has raised hopes for the treatment of pediatric malignancies. Although CAR T-cell development is on a fast-moving pace and evolution, the context of exploring novel targetable antigens has been neglected. In this review study, we analyze the prominent hematologic antigens targeted by engineered T-...

An Update of Pharmacological & Non-Pharmacological Therapies for COVID-19 Pandemic Trivia

The whole planet is facing one of the scariest pandemic situations in this era. On 11th February, 2020 the World Health Organization announced the name of an unknown disease as COVID-19, which is caused by the ssRNA virus SARS-CoV-2 (formally recognized as a sister of SARS-CoV and MERS-CoV). The epicenter of this disease is Wuhan, Hubei Province, China. COVID-19 can affect all age groups but pa...

An update on current concepts of the epidemiology of bovine Pestivirus infection in cattle

An interior-point algorithm for $P_{ast}(kappa)$-linear complementarity problem based on a new trigonometric kernel function

In this paper, an interior-point algorithm  for $P_{ast}(kappa)$-Linear Complementarity Problem (LCP) based on a new parametric trigonometric kernel function is proposed. By applying strictly feasible starting point condition and using some simple analysis tools, we prove that our algorithm has $O((1+2kappa)sqrt{n} log nlogfrac{n}{epsilon})$ iteration bound for large-update methods, which coinc...

HYBRID COLLIDING BODIES OPTIMIZATION AND SINE COSINE ALGORITHM FOR OPTIMUM DESIGN OF STRUCTURES

Colliding Bodies Optimization (CBO) is a population-based metaheuristic algorithm that complies physics laws of momentum and energy. Due to the stagnation susceptibility of CBO by premature convergence and falling into local optima, some meritorious methodologies based on Sine Cosine Algorithm and a mutation operator were considered to mitigate the shortcomings mentioned earlier. Sine Cosine Al...